BDBM556970 US11352340, Example 1

SMILES Clc1ccc(Cn2cc(cn2)-c2ccnc(c2)-c2ncc([nH]2)-c2ccccc2)cc1

InChI Key InChIKey=PKRKUSOJUONPPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 556970   

TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 50nMAssay Description:Inhibition of P13Kgamma (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 500nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent