BDBM557131 2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 5-[(3- phenylpyrrolidin-::US11352340, Example 181

SMILES Cc1nc(-c2cc(-c3cncc(C(=O)N4CCC(c5ccccc5)C4)c3)ccn2)[nH]c1C

InChI Key InChIKey=NOEQDOZDLVPJEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557131   

LigandChemical structure of BindingDB Monomer ID 557131BDBM557131(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 5-[(3- pheny...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 557131BDBM557131(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 5-[(3- pheny...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent