BDBM557603 (2-((1-(6-Fluorobenzo[d]thiazol-2-yl)indolin-4-yl)oxy)pyridin-4-yl)methanamine hydrochloride ::US11358936, Compound 2-33

SMILES NCc1ccnc(Oc2cccc3N(CCc23)c2nc3ccc(F)cc3s2)c1

InChI Key InChIKey=IOWVFWHDGIWANZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557603   

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM557603(US11358936, Compound 2-33 | (2-((1-(6-Fluorobenzo[...)
Affinity DataIC50: 300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2022
Entry Details
US Patent