BDBM558820 Isomer 1 of 1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-3-((1-::US11365205, Example 84a

SMILES Cn1cnc2ccc(Cn3c4ccccc4n(C[C@H](O)CN4CCc5ccccc5C4)c3=O)cc12

InChI Key InChIKey=DTFULKURTJXYSJ-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558820   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558820(Isomer 1 of 1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)...)
Affinity DataIC50:  10nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent