BDBM559836 US11376258, Example 2

SMILES Cc1ncnc2[nH]c(C3CN(C(=O)OCc4c(F)cccc4F)CCO3)nc12

InChI Key InChIKey=ULLNCMOQDODFSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559836   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 559836BDBM559836(US11376258, Example 2)
Affinity DataIC50: 427nMAssay Description:At the assay day cells were washed 3× with assay buffer, 10 μL buffer remained in the wells after washing. 10 μL Ca kit loading buffer (AAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent