BDBM559852 US11376258, Example 24

SMILES O=C(OCc1ccc(C(F)F)cc1)N1CCOC(c2nc3cncnc3[nH]2)C1

InChI Key InChIKey=GYKCGTDQBILQPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559852   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 559852BDBM559852(US11376258, Example 24)
Affinity DataIC50: 45nMAssay Description:At the assay day cells were washed 3× with assay buffer, 10 μL buffer remained in the wells after washing. 10 μL Ca kit loading buffer (AAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent