BDBM560078 US11377438, Example 120

SMILES C[C@H]1CN(CC[C@@H](O1)C(F)(F)F)c1ncc(cc1C(=O)Nc1ccnc(c1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=AKIRCBOCGBUWFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560078   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560078(US11377438, Example 120)
Affinity DataIC50: 2.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent