BDBM560624 US11384066, Example 1

SMILES Cc1cc(Nc2ccc(F)c(CC3(CCN(Cc4cccc(Cl)c4F)CC3)C(O)=O)n2)n[nH]1

InChI Key InChIKey=LGTBIYHSNLXDIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560624   

TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560624(US11384066, Example 1)
Affinity DataIC50:  2.97E+3nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560624(US11384066, Example 1)
Affinity DataIC50:  1.30nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent