BDBM560942 US11390610, Example 1::US11390610, Example 160

SMILES CC(=O)N(CCc1ccc(C(=O)N2CCN(c3nc4ccccc4c(=O)[nH]3)CC2)cc1)Cc1cccc(C(F)(F)F)c1

InChI Key InChIKey=MLKDZCXOEZOMMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560942   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 560942BDBM560942(US11390610, Example 1 | US11390610, Example 160)
Affinity DataIC50: 20nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 560942BDBM560942(US11390610, Example 1 | US11390610, Example 160)
Affinity DataIC50: 49nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent