BDBM560969 US11390610, Example 17

SMILES O=C(c1ccc(-c2cccc(C(F)(F)F)c2)cc1)N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=CYVDGZXYYIQBDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560969   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 560969BDBM560969(US11390610, Example 17)
Affinity DataIC50: 36nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent