BDBM561034 US11390610, Example 73

SMILES Cc1cc(C(=O)N2CCN(c3nc4ccccc4c(=O)[nH]3)CC2)ccc1OCc1cccc(Cl)c1

InChI Key InChIKey=BWHWGWMALFEWMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561034   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 561034BDBM561034(US11390610, Example 73)
Affinity DataIC50: 20nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent