BDBM561039 US11390610, Example 76

SMILES O=C(c1ccc(OCc2cccc(Cl)c2)c(-c2ncc[nH]2)c1)N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=QWQCYDKKJDDNFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561039   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 561039BDBM561039(US11390610, Example 76)
Affinity DataIC50: 33nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent