BDBM561346 2-[4-[3-Chloro-4-[(4-chloropyridin-2-yl)methoxy]benzoyl]piperazin-1-yl]-3H-quinazolin-4-one::US11390610, Example 175

SMILES O=C(c1ccc(OCc2cc(Cl)ccn2)c(Cl)c1)N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=GFTJRWUNSWOILU-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561346   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 561346BDBM561346(US11390610, Example 175 | 2-[4-[3-Chloro-4-[(4-chl...)
Affinity DataIC50: 48nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent