BDBM561366 2-[4-[3-(3-Chlorophenyl)sulfonyl-3,9-diazaspiro[5.5]undecane-9-carbonyl]piperazin-1-yl]-3H-quinazolin-4-one::US11390610, Example 195

SMILES O=C(N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1)N1CCC2(CC1)CCN(S(=O)(=O)c1cccc(Cl)c1)CC2

InChI Key InChIKey=VUFQVBRKAYTKMT-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561366   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 561366BDBM561366(US11390610, Example 195 | 2-[4-[3-(3-Chlorophenyl)...)
Affinity DataIC50: 34nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent