BDBM561382 US11390610, Example 211

SMILES CC(C)(COCc1ccccc1)c1nc(-c2ccc(C(=O)N3CCN(c4nc5ccccc5c(=O)[nH]4)CC3)cc2)no1

InChI Key InChIKey=KLCLFHNOILSWNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561382   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 561382BDBM561382(US11390610, Example 211)
Affinity DataIC50: 11nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent