BDBM561432 3-(4-amino-7-(4-methyloxazol-5-yl)-2-(1-(pyridin-2-yl)ethyl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile::US11390624, Example 46

SMILES Cc1ncoc1-c1c(-c2cccc(C#N)c2)nc(N)c2nn(C(C)c3ccccn3)nc12

InChI Key InChIKey=QERMAYDOJNPKTF-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561432   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 561432BDBM561432(US11390624, Example 46 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 561432BDBM561432(US11390624, Example 46 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent