BDBM5615 2-(4-hydroxypiperidin-1-yl)-N-{3-[4-(morpholin-4-yl)phenyl]-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide::3-(4-Morpholinophenyl)-5-(4-hydroxypiperidinoacetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 8f

SMILES O=C(CN1CCC(O)CC1)Nc1cccc2c1C(=O)c1c-2n[nH]c1-c1ccc(N2CCOCC2)cc1

InChI Key InChIKey=LEKQENSPYUBVKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5615   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5615BDBM5615(2-(4-hydroxypiperidin-1-yl)-N-{3-[4-(morpholin-4-y...)
Affinity DataIC50: 85nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5615BDBM5615(2-(4-hydroxypiperidin-1-yl)-N-{3-[4-(morpholin-4-y...)
Affinity DataIC50: 110nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed