BDBM5617 2-(4-methylpiperazin-1-yl)-N-{3-[4-(morpholin-4-yl)phenyl]-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide::3-(4-Morpholinophenyl)-5-((4-methylpiperazino)acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 8h

SMILES CN1CCN(CC(=O)Nc2cccc3c2C(=O)c2c-3n[nH]c2-c2ccc(N3CCOCC3)cc2)CC1

InChI Key InChIKey=STWGJFWWXVBMEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5617   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5617BDBM5617(3-(4-Morpholinophenyl)-5-((4-methylpiperazino)acet...)
Affinity DataIC50: 42nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5617BDBM5617(3-(4-Morpholinophenyl)-5-((4-methylpiperazino)acet...)
Affinity DataIC50: 190nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed