BDBM562031 (S)-N-Cyclobutyl-2-(4-(2-(1- cyclopropylethyl)-7- (methylsulfonyl)-1- oxoisoindolin-5-yl)pyridin-2-yl)- N,4-dimethyl-1H-imidazole-5- carboxamide, trifluoroacetate salt::US11396502, Example 7u

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1ccnc(c1)-c1nc(C)c([nH]1)C(=O)N(C)C1CCC1

InChI Key InChIKey=LHEKDDOAOMDMDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562031   

LigandPNGBDBM562031(US11396502, Example 7u | (S)-N-Cyclobutyl-2-(4-(2-...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM562031(US11396502, Example 7u | (S)-N-Cyclobutyl-2-(4-(2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent