BDBM562037 (S)-2-(1-Cyclopropyl- ethyl)-5-(2-(5-methyl- 4H-1,2,4-triazol-3-yl) pyridin-4-yl)isoindo- lin-1-one::US11396502, Example 13

SMILES C[C@@H](C1CC1)N1Cc2cc(ccc2C1=O)-c1ccnc(c1)-c1nnc(C)[nH]1

InChI Key InChIKey=ZKUQORLDQGFVSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562037   

LigandPNGBDBM562037(US11396502, Example 13 | (S)-2-(1-Cyclopropyl- eth...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM562037(US11396502, Example 13 | (S)-2-(1-Cyclopropyl- eth...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent