BDBM562227 1-([1,1′-bi(cyclopropan)]-1-yl)-5-propyl-6,7,8,9-tetrahydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one::US11401274, Example 1
SMILES CCCn1c2CCCCc2n2c(nnc2c1=O)C1(CC1)C1CC1
InChI Key InChIKey=ZOYWVKURDMXZTC-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 562227
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 2.90nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 3.10nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 3.30nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair