BDBM562229 1-([1,1′-bi(cyclopropan)]-1-yl)-5-(cyclopropylmethyl)-5,6,7,9-tetrahydro-4H-pyrano[4,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-one::US11401274, Example 3
SMILES O=c1n(CC2CC2)c2CCOCc2n2c(nnc12)C1(CC1)C1CC1
InChI Key InChIKey=VGHIZNBWVGBFNE-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 562229
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 9.80nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 8.70nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+4nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 6.80nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair