BDBM562239 1-([1,1′-bi(cyclopropan)]-1-yl)-5-butyl-8,9-dihydro-6H-pyrano[3,4-e][1,2,4]triazolo[4,3-a]pyrazin-4(5H)-one::US11401274, Example 7
SMILES CCCCn1c2COCCc2n2c(nnc2c1=O)C1(CC1)C1CC1
InChI Key InChIKey=OTQSGQJYNNQNSN-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 562239
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 5.20nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 12nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Eli Lilly
US Patent
Eli Lilly
US Patent
Affinity DataIC50: 2.70nMAssay Description:All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio...More data for this Ligand-Target Pair