BDBM562327 (S)-4-(2-fluoro-4-(1-(2- fluorophenyl)-3- (methylamino)propoxy) benzyl)-1-methyl-1,2,3,4- tetrahydro-5H- pyrido[2,3- e][1,4]diazepin-5-one::US11401270, Example 152

SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1ccccc1F

InChI Key InChIKey=ZNXDCXZJXFKNJJ-DEOSSOPVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562327   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562327((S)-4-(2-fluoro-4-(1-(2- fluorophenyl)-3- (methyla...)
Affinity DataKi: <100nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562327((S)-4-(2-fluoro-4-(1-(2- fluorophenyl)-3- (methyla...)
Affinity DataKi: <100nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562327((S)-4-(2-fluoro-4-(1-(2- fluorophenyl)-3- (methyla...)
Affinity DataKi: <100nMAssay Description:Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent