BDBM562351 (rac)-13-Chloro-12-ethyl-1-(34(4-fluoronaphthalen-1-yl)oxy)propyl)-8,11-dimethyl-4,5,6,8,9,11-hexahydropyrazolo[3′,4′:4,5][1,2,8]thiadiazacycloundecino[6,7,8-hi]indole-2-carboxylic acid 7,7-dioxide::US11401278, Example 24

SMILES CCc1c-2c(CN(C)S(=O)(=O)CCCn3c(C(O)=O)c(CCCOc4ccc(F)c5ccccc45)c4ccc(Cl)c-2c34)nn1C

InChI Key InChIKey=BTWHAJJIYQNJBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562351   

LigandPNGBDBM562351((rac)-13-Chloro-12-ethyl-1-(34(4-fluoronaphthalen-...)
Affinity DataIC50:  3.40nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM562351((rac)-13-Chloro-12-ethyl-1-(34(4-fluoronaphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-XL/Bad BH3 Peptide (BCL-XL Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-XL solution (usually for a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM562351((rac)-13-Chloro-12-ethyl-1-(34(4-fluoronaphthalen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent