BDBM563033 US11407736, Compound II-27::US11578078, Compound I-5

SMILES CN1CCC2(CC1)CCN(CC2)c1ccc2OC[C@H](NC(=O)c3cc(Oc4ccccc4)ccn3)C(=O)N(C)c2c1

InChI Key InChIKey=IWNOTZKOESCXDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563033   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563033(US11407736, Compound II-27 | US11578078, Compound ...)
Affinity DataIC50: 27.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563033(US11407736, Compound II-27 | US11578078, Compound ...)
Affinity DataIC50: 27.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent