BDBM5632 2-[4-(aminomethyl)piperidin-1-yl]-N-[4-oxo-3-(propan-2-yl)-2H,4H-indeno[1,2-c]pyrazol-5-yl]acetamide::3-Isopropyl-5-(4-(aminomethyl)piperidinoacetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 13o

SMILES CC(C)c1[nH]nc2c1C(=O)c1c(NC(=O)CN3CCC(CN)CC3)cccc1-2

InChI Key InChIKey=RABZCZVASTTWML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5632   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5632BDBM5632(2-[4-(aminomethyl)piperidin-1-yl]-N-[4-oxo-3-(prop...)
Affinity DataIC50: 48nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5632BDBM5632(2-[4-(aminomethyl)piperidin-1-yl]-N-[4-oxo-3-(prop...)
Affinity DataIC50: 340nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed