BDBM563321 4-[6-{[(2-hydroxyethyl)amino]methyl}-2-(2-methylbiphenyl-3-yl)[1,2,4]triazolo[1,5-a]pyridin-8-yl]butanenitrile::US11407749, Example 23

SMILES Cc1c(cccc1-c1ccccc1)-c1nc2c(CCCC#N)cc(CNCCO)cn2n1

InChI Key InChIKey=NSSXZYBLHNZUMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563321   

LigandPNGBDBM563321(4-[6-{[(2-hydroxyethyl)amino]methyl}-2-(2-methylbi...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
US Patent