BDBM565105 N-(1-cyanopyrrolidin-3-yl)-4-((5- (trifluoromethyl)pyridin-2- yl)oxy)benzenesulfonamide::US11414402, Example 19

SMILES FC(F)(F)c1ccc(Oc2ccc(cc2)S(=O)(=O)NC2CCN(C2)C#N)nc1

InChI Key InChIKey=KWAQJZBRETZPOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 565105   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM565105(US11414402, Example 19 | N-(1-cyanopyrrolidin-3-yl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM565105(US11414402, Example 19 | N-(1-cyanopyrrolidin-3-yl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent