BDBM5652 3-(Furan-2-yl)-5-(carbamoylamino)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 24l::[3-(furan-2-yl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]urea

SMILES NC(=O)Nc1cccc2c1C(=O)c1c(-c3ccco3)n[nH]c1-2

InChI Key InChIKey=YBPLYSSLKULVHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5652   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5652BDBM5652(3-(Furan-2-yl)-5-(carbamoylamino)indeno[1,2-c]pyra...)
Affinity DataIC50: 86nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 5652BDBM5652(3-(Furan-2-yl)-5-(carbamoylamino)indeno[1,2-c]pyra...)
Affinity DataIC50: 840nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed