BDBM565617 US11414431, Compound I-183

SMILES CNc1cc(Nc2cccn([C@H]3CCC[C@H]3O)c2=O)nc2c(cnn12)C(=O)N[C@H]1CC[C@@H]1F

InChI Key InChIKey=TWJSWHXNOJQECY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 565617   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM565617(US11414431, Compound I-183)
Affinity DataKd:  0.600nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent