BDBM566468 N-(1S)-2-hydroxy-2- methyl-1-(4- (trifluoromethoxy)- phenyl)propyl)-5-(4- methyl-1H-1,2,3- triazol-1- yl)pyrazolo[1,5-a] pyrimidine-3- carboxamide::US11419874, Example 18

SMILES Cc1cn(nn1)-c1ccn2ncc(C(=O)N[C@@H](c3ccc(OC(F)(F)F)cc3)C(C)(C)O)c2n1

InChI Key InChIKey=YMVMHAWCGXLTFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 566468   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566468(US11419874, Example 18 | N-(1S)-2-hydroxy-2- methy...)
Affinity DataIC50: 5.40nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
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Date in BDB:
11/6/2022
Entry Details
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