BDBM567976 US11420970, Example 177

SMILES COC(=O)NC1(CCCN(C1)c1cnc(cc1Cn1cnc2c(ncnc12)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)-c1ccc(F)c(F)c1)c1cccc(C)n1

InChI Key InChIKey=FHGOSDAYQXVDBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 567976   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandPNGBDBM567976(US11420970, Example 177)
Affinity DataIC50: 5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent