BDBM568125 US11420973, Example 2

SMILES COc1ccc(-c2[nH]c3ccc(C(=O)N4CCCN(C)CC4)cc3c2C(C)C)cc1OC

InChI Key InChIKey=ZOQVKODCNAEOGU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 568125   

TargetToll-like receptor 8(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568125BDBM568125(US11420973, Example 2)
Affinity DataIC50: 4nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568125BDBM568125(US11420973, Example 2)
Affinity DataIC50: 45nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetToll-like receptor 9(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568125BDBM568125(US11420973, Example 2)
Affinity DataIC50: 3.01E+3nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent