BDBM568160 US11420973, Example 37

SMILES CCc1c(-c2ccc(OC)c(OC)c2)[nH]c2ccc(C(=O)N3CCN(CCc4ccccc4)CC3)cc12

InChI Key InChIKey=XLTFFAZSAHKKPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 568160   

TargetToll-like receptor 8(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568160BDBM568160(US11420973, Example 37)
Affinity DataIC50: 14nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568160BDBM568160(US11420973, Example 37)
Affinity DataIC50: 1.30E+3nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetToll-like receptor 9(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 568160BDBM568160(US11420973, Example 37)
Affinity DataIC50: 9.94E+3nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent