BDBM5682 2-amino-5-thio-substituted thiazole 27::N-(5-{[(5-phenyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)acetamide::N-[5-[[[5-Phenyl-2-oxazolyl]methyl]thio]-2-thiazolyl]acetamide

SMILES CC(=O)Nc1ncc(SCc2ncc(o2)-c2ccccc2)s1

InChI Key InChIKey=QCLGQMKUDBLDML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5682   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5682(N-[5-[[[5-Phenyl-2-oxazolyl]methyl]thio]-2-thiazol...)
Affinity DataIC50: 350nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5682(N-[5-[[[5-Phenyl-2-oxazolyl]methyl]thio]-2-thiazol...)
Affinity DataIC50: 4.51E+3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed