BDBM568368 US11420975, Compound A-10-22

SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)C12CCC(CC1)(C2)NC(=O)c1nccs1

InChI Key InChIKey=MFFYARSBDVGVCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568368   

TargetTyrosine-protein kinase BTK [C481S](Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568368(US11420975, Compound A-10-22)
Affinity DataIC50:  5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTyrosine-protein kinase BTK(Human)
TRANSTHERA SCIENCES (NANJING), INC.

US Patent
LigandPNGBDBM568368(US11420975, Compound A-10-22)
Affinity DataIC50:  5.5nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent