BDBM568451 US11420984, Example 1

SMILES OB(O)CCCC[C@@]1(CCCN1)C(O)=O

InChI Key InChIKey=PUGJOOXDLAIKFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 568451   

TargetArginase-1(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetArginase-1(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 1.47E+4nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetArginase-1(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 568451BDBM568451(US11420984, Example 1)
Affinity DataIC50: 2.30E+4nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent