BDBM568462 US11420984, Example 12

SMILES O=C(N[C@H]1CN[C@@](CCCCB(O)O)(C(=O)O)C1)[C@@H]1CCCN1

InChI Key InChIKey=KPODRVSPCSAVDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 568462   

TargetArginase-1(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 568462BDBM568462(US11420984, Example 12)
Affinity DataIC50: 700nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetArginase-1(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 568462BDBM568462(US11420984, Example 12)
Affinity DataIC50: 768nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetArginase-2, mitochondrial(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 568462BDBM568462(US11420984, Example 12)
Affinity DataIC50: 850nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent