BDBM568580 (6S)-5-(3-Fluoro-4-morpholinophenyl)-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 25-1

SMILES C[C@@H]1OC(=O)NN=C1c1ccc(N2CCOCC2)c(F)c1

InChI Key InChIKey=CTSRYFMXFGZHJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568580   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568580((6S)-5-(3-Fluoro-4-morpholinophenyl)-6-methyl-3,6-...)
Affinity DataIC50: 22nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568580((6S)-5-(3-Fluoro-4-morpholinophenyl)-6-methyl-3,6-...)
Affinity DataIC50: 44nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent