BDBM568655 5-[3-Fluoro-4-(pyridin-3-yl)phenyl]-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 108

SMILES Fc1cc(ccc1-c1cccnc1)C1=NNC(=O)OC1

InChI Key InChIKey=UQYJCNPSDZVFDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568655   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
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US Patent
LigandPNGBDBM568655(5-[3-Fluoro-4-(pyridin-3-yl)phenyl]-3,6-dihydro-2H...)
Affinity DataIC50: 22nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568655(5-[3-Fluoro-4-(pyridin-3-yl)phenyl]-3,6-dihydro-2H...)
Affinity DataIC50: 26nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent