BDBM568667 (6S)-6-Methyl-5-[4-(morpholin-4-yl)-3-(trifluoromethyl)phenyl]-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 120

SMILES C[C@@H]1OC(=O)NN=C1c1ccc(N2CCOCC2)c(C)c1

InChI Key InChIKey=IKINZRGKBOIIQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568667   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568667((6S)-6-Methyl-5-[4-(morpholin-4-yl)-3-(trifluorome...)
Affinity DataIC50: 4nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568667((6S)-6-Methyl-5-[4-(morpholin-4-yl)-3-(trifluorome...)
Affinity DataIC50: 6nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent