BDBM568808 (rac)-5-{4-[Oxan-3-yl]-3-(trifluoromethyl)phenyl}-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 271

SMILES FC(F)(F)c1cc(ccc1C1CCCOC1)C1=NNC(=O)OC1

InChI Key InChIKey=OJNOGIOWPRIKOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568808   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568808((rac)-5-{4-[Oxan-3-yl]-3-(trifluoromethyl)phenyl}-...)
Affinity DataIC50: 25nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568808((rac)-5-{4-[Oxan-3-yl]-3-(trifluoromethyl)phenyl}-...)
Affinity DataIC50: 27nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent