BDBM568850 5-[4-(2-methyl-1H-benzimidazol-5-yl)-3-(trifluoromethyl)phenyl]-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 326

SMILES Cc1nc2cc(ccc2[nH]1)-c1ccc(cc1C(F)(F)F)C1=NNC(=O)OC1

InChI Key InChIKey=HYFPAHQYPCEVQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 568850   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
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US Patent
LigandPNGBDBM568850(5-[4-(2-methyl-1H-benzimidazol-5-yl)-3-(trifluorom...)
Affinity DataIC50: 17nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM568850(5-[4-(2-methyl-1H-benzimidazol-5-yl)-3-(trifluorom...)
Affinity DataIC50: 30nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent