BDBM569844 (+/−)-4-(2,6-difluoro-4-{[5-(hydroxymethyl)-5-methyl-5,6-dihydro-4H-1,3-oxazin-2-yl]amino}phenoxy)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile::US11427578, Example 17

SMILES CC1(CO)COC(Nc2cc(F)c(Oc3ccnc4[nH]cc(C#N)c34)c(F)c2)=NC1

InChI Key InChIKey=VDDCDSSPBMTXEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569844   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM569844((+/−)-4-(2,6-difluoro-4-{[5-(hydroxymethyl)-...)
Affinity DataIC50: 960nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM569844((+/−)-4-(2,6-difluoro-4-{[5-(hydroxymethyl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent