BDBM569885 (+/−)-[2-(2,5-difluoro-4-{[3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy}anilino)-5-methyl-5,6-dihydro-4H-1,3-oxazin-5-yl]methanol::US11427578, Example 58

SMILES CC1(CO)COC(Nc2cc(F)c(Oc3ccnc4[nH]cc(c34)C(F)(F)F)cc2F)=NC1

InChI Key InChIKey=KYRMTCXDVSWSMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 569885   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM569885((+/−)-[2-(2,5-difluoro-4-{[3-(trifluoromethy...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent