BDBM569913 (+/−)-2-[4-(2,6-difluoro-4-{[5-(hydroxymethyl)-5-methyl-5,6-dihydro-4H-1,3-oxazin-2-yl]amino}phenoxy)-1H-pyrrolo[2,3-b]pyridin-3-yl]-6-methoxybenzonitrile::US11427578, Example 86

SMILES COc1cccc(-c2c[nH]c3nccc(Oc4c(F)cc(NC5=NCC(C)(CO)CO5)cc4F)c23)c1C#N

InChI Key InChIKey=YVAAIJLZJOPDGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569913   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM569913((+/−)-2-[4-(2,6-difluoro-4-{[5-(hydroxymethy...)
Affinity DataIC50: 1.90E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM569913((+/−)-2-[4-(2,6-difluoro-4-{[5-(hydroxymethy...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent