BDBM570091 US11427590, Entry 8::US20240115574, Entry 8

SMILES COC(=O)c1ccc(cc1F)-c1c(C)nc2c(cc(C)nn12)N1CC[C@H](C1)NC(C)=O

InChI Key InChIKey=KCNZEWYZGFASPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 570091   

TargetSphingomyelin phosphodiesterase 3(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM570091(US11427590, Entry 8 | US20240115574, Entry 8)
Affinity DataIC50: 400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM570091(US11427590, Entry 8 | US20240115574, Entry 8)
Affinity DataIC50: 400nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent