BDBM570784 US11440886, Example 115

SMILES COc1ccc(cc1OC)C(=C\n1c(C)cc(=O)cc1C)\C#N

InChI Key InChIKey=HELWEYXBZUMESD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570784   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
E-Nitiate Biopharmaceuticals (Hangzhou)

US Patent
LigandPNGBDBM570784(US11440886, Example 115)
Affinity DataIC50: 9.90nMAssay Description:The inhibitory effect of the compounds on human PDE4B1 enzyme activity was determined by quantifying the 5′-adenosine monophosphate (5′-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent