BDBM5708 2-amino-5-thio-substituted thiazole 76::N-(5-{[(2-tert-butyl-1,3-oxazol-5-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-2-phenylacetamide

SMILES CC(C)(C)c1ncc(CSc2cnc(NC(=O)Cc3ccccc3)s2)o1

InChI Key InChIKey=RETDFEDFSXGWJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5708   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5708(N-(5-{[(2-tert-butyl-1,3-oxazol-5-yl)methyl]sulfan...)
Affinity DataIC50: 3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed